Angiotensin Receptor Blockers
How do AT1-receptor blockers work? According to the mechanism of action, angiotensin receptor blockers (BAR), as well as ACE inhibitors, affect the ReninAngiotensin system. However, this class works “more targeted”, since it removes the excess effects of angiotensin and aldosterone by blocking the at-receptors that these Pressor (blood PRESSURE-boosting) agents affect. THEY prevent the formation of angiotensin, a substance that causes vasoconstriction, and the vessels expand. As a result, blood pressure decreases. What are AT1-receptor blockers? Currently, there are a…