Blockers of alpha1-adrenoreceptors (alpha1-blockers)

Blockers of alpha1-adrenoreceptors (alpha1-blockers)

How do alpha-1 blockers work?

Drugs of this group block the receptors (nerve endings) to epinephrine located in the blood vessels, and prevent the action of vasoconstrictors (in particular, epinephrine).

As a result, blood vessels expand and blood pressure decreases.

What are the different types of alpha1 blockers?

There are only 3 drugs of this group. Their main difference is the duration of the action. Short-acting drugs include prazosin, long-acting drugs-doxazosin and terazosin.

What are alpha1 blockers good for?

Alpha 1 blockers reduce blood pressure well.

In addition, they reduce the content of cholesterol in the blood, have a beneficial effect on carbohydrate metabolism, increasing the effect of insulin.

It is also important that these medications affect the prostate and bladder, and facilitate urination in patients with prostate adenoma.

In what cases does the doctor prescribe alpha 1 blockers?

Alpha 1 blockers are excluded from first-choice medications.

They are prescribed to patients with prostate adenoma, diabetes, overweight, increased cholesterol in the blood.

When can I not prescribe alpha 1 blockers?

Alpha 1 blockers are not recommended for heart failure. Pregnant and nursing women should not take these medications.

Be sure to tell your doctor:

• Whether you have taken alpha1 blockers before, and how You have reacted to them.

• Whether you have liver changes detected.

How should I take alpha 1 blockers?

Special care is required for the first intake of the drug. It is necessary to observe bed rest for 1-2 hours, as when getting out of bed, a sharp decrease in blood pressure may occur. Drugs of this group interact with alcohol, so you should avoid alcoholic beverages.

What adverse reactions are possible when taking alpha 1 blockers?

When treated with these drugs, headache, dizziness, sleep disorders, weakness, fatigue, nausea, palpitations, rapid urination are possible. With prolonged use, there are swelling of the feet and shins. In rare cases (especially when taking the drug for the first time and after taking alcohol), the so-called orthostatic reaction is possible (sudden weakness, dizziness up to loss of balance when changing the position of the body). It is necessary to strictly observe the recommended dose and time of taking the drug.

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